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Folic-acid-conjugated pullulan/poly(DL-lactide-co-glycolide) graft copolymer nanoparticles for folate-receptor-mediated drug delivery

BACKGROUND: Nanoparticles have been extensively investigated for targeted delivery of anticancer drugs. Since the folate receptor is universally over-expressed on the tumor cell membrane, folic acid is often used to modify the fate of nanoparticles in biologicals. METHODS: To fabricate targetable na...

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Detalhes bibliográficos
Publicado no:Nanoscale Res Lett
Main Authors: Lee, Sang Joon, Shim, Yong-Ho, Oh, Jong-Suk, Jeong, Young-Il, Park, In-Kyu, Lee, Hyun Chul
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384989/
https://ncbi.nlm.nih.gov/pubmed/25852340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11671-014-0706-1
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