Sex Affects Bone Morphogenetic Protein Type II Receptor Signaling in Pulmonary Artery Smooth Muscle Cells

Rationale: Major pulmonary arterial hypertension (PAH) registries report a greater incidence of PAH in women; mutations in the bone morphogenic protein type II receptor (BMPR-II) occur in approximately 80% of patients with heritable PAH (hPAH). Objectives: We addressed the hypothesis that women may...

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Publicado en:Am J Respir Crit Care Med
Main Authors: Mair, Kirsty M., Yang, Xu Dong, Long, Lu, White, Kevin, Wallace, Emma, Ewart, Marie-Ann, Docherty, Craig K., Morrell, Nicholas W., MacLean, Margaret R.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2015
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384779/
https://ncbi.nlm.nih.gov/pubmed/25608111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201410-1802OC
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