Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex

Endothelial responses to fluid shear stress are essential for vascular development and physiology, and determine the formation of atherosclerotic plaques at regions of disturbed flow. Previous work identified VE-cadherin as an essential component, along with PECAM-1 and VEGFR2, of a complex that med...

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發表在:J Cell Biol
Main Authors: Coon, Brian G., Baeyens, Nicolas, Han, Jinah, Budatha, Madhusudhan, Ross, Tyler D., Fang, Jennifer S., Yun, Sanguk, Thomas, Jeon-Leon, Schwartz, Martin A.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2015
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384728/
https://ncbi.nlm.nih.gov/pubmed/25800053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408103
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