Role of RhoB in the Regulation of Pulmonary Endothelial and Smooth Muscle Cell Responses to Hypoxia

RATIONALE: RhoA and Rho kinase contribute to pulmonary vasoconstriction and vascular remodeling in pulmonary hypertension. RhoB, a protein homologous to RhoA and activated by hypoxia, regulates neoplastic growth and vasoconstriction but its role in the regulation of pulmonary vascular function is no...

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Bibliographic Details
Published in:Circ Res
Main Authors: Wojciak-Stothard, Beata, Zhao, Lan, Oliver, Eduardo, Dubois, Olivier, Wu, Yixing, Kardassis, Dimitris, Vasilaki, Eleftheria, Huang, Minzhou, Mitchell, Jane A., Harrington, Louise S., Prendergast, George C., Wilkins, Martin R.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384697/
https://ncbi.nlm.nih.gov/pubmed/22539766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.264473
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