Increased Sclerostin Levels after Further Ablation of Remnant Estrogen by Aromatase Inhibitors

BACKGROUND: Sclerostin is a secreted Wnt inhibitor produced almost exclusively by osteocytes, which inhibits bone formation. Aromatase inhibitors (AIs), which reduce the conversion of steroids to estrogen, are used to treat endocrine-responsive breast cancer. As AIs lower estrogen levels, they incre...

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Detalhes bibliográficos
Publicado no:Endocrinol Metab (Seoul)
Main Authors: Kim, Wonjin, Chung, Yoonjung, Kim, Se Hwa, Park, Sehee, Bae, Jae Hyun, Kim, Gyuri, Lee, Su Jin, Kim, Jo Eun, Park, Byeong-Woo, Lim, Sung-Kil, Rhee, Yumie
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Endocrine Society 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384667/
https://ncbi.nlm.nih.gov/pubmed/25827459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3803/EnM.2015.30.1.58
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