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Increased Sclerostin Levels after Further Ablation of Remnant Estrogen by Aromatase Inhibitors
BACKGROUND: Sclerostin is a secreted Wnt inhibitor produced almost exclusively by osteocytes, which inhibits bone formation. Aromatase inhibitors (AIs), which reduce the conversion of steroids to estrogen, are used to treat endocrine-responsive breast cancer. As AIs lower estrogen levels, they incre...
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| Pubblicato in: | Endocrinol Metab (Seoul) |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Korean Endocrine Society
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4384667/ https://ncbi.nlm.nih.gov/pubmed/25827459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3803/EnM.2015.30.1.58 |
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