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Redox modification of nuclear actin by MICAL-2 regulates SRF signaling
The serum response factor (SRF) binds to coactivators, such as myocardin-related transcription factor-A (MRTF-A), and mediates gene transcription elicited by diverse signaling pathways. SRF/MRTF-A-dependent gene transcription is activated when nuclear MRTF-A levels increase, enabling the formation o...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4384661/ https://ncbi.nlm.nih.gov/pubmed/24440334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.12.035 |
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