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Effect of airway acidosis and alkalosis on airway vascular smooth muscle responsiveness to albuterol
BACKGROUND: In vitro and animal experiments have shown that the transport and signaling of β(2)-adrenergic agonists are pH-sensitive. Inhaled albuterol, a hydrophilic β(2)-adrenergic agonist, is widely used for the treatment of obstructive airway diseases. Acute exacerbations of obstructive airway d...
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| Veröffentlicht in: | BMC Pharmacol Toxicol |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4384333/ https://ncbi.nlm.nih.gov/pubmed/25889594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-015-0008-y |
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