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Regulated protein turnover: snapshots of the proteasome in action
The ubiquitin-proteasome system (UPS) is the main ATP-dependent protein degradation pathway in the cytosol and nucleus of eukaryotic cells. At its centre is the 26S proteasome, which degrades regulatory proteins and mis-folded or damaged proteins. In a major breakthrough, several groups have determi...
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| Publicat a: | Nat Rev Mol Cell Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4384331/ https://ncbi.nlm.nih.gov/pubmed/24452470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3741 |
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