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MARZ: an algorithm to combinatorially analyze gapped n-mer models of transcription factor binding

BACKGROUND: A key challenge in understanding the molecular mechanisms that control gene regulation is the characterization of the specificity with which transcription factor proteins bind to specific DNA sequences. A number of computational approaches have been developed to examine these interaction...

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Publicado en:BMC Bioinformatics
Autores principales: Zellers, Rowan G, Drewell, Robert A, Dresch, Jacqueline M
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384306/
https://ncbi.nlm.nih.gov/pubmed/25637281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-014-0446-3
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