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Chronic wheel running-induced reduction of extinction and reinstatement of methamphetamine seeking in methamphetamine dependent rats is associated with reduced number of periaqueductal gray dopamine neurons

Exercise (physical activity) has been proposed as a treatment for drug addiction. In rodents, voluntary wheel running reduces cocaine and nicotine seeking during extinction, and reinstatement of cocaine seeking triggered by drug cues. The purpose of this study was to examine the effects of chronic w...

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Publicat a:Brain Struct Funct
Autors principals: Sobieraj, Jeffery C., Kim, Airee, Fannon, McKenzie J., Mandyam, Chitra D.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383734/
https://ncbi.nlm.nih.gov/pubmed/25273280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-014-0905-7
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