Sex Differences in Context-Driven Reinstatement of Methamphetamine Seeking is Associated with Distinct Neuroadaptations in the Dentate Gyrus

The present study examined differences in operant responses in adult male and female rats during distinct phases of addiction. Males and females demonstrated escalation in methamphetamine (0.05 mg/kg, i.v.) intake with females showing enhanced latency to escalate, and bingeing. Following protracted...

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Udgivet i:Brain Sci
Main Authors: Takashima, Yoshio, Tseng, Joyee, Fannon, McKenzie J., Purohit, Dvijen C., Quach, Leon W., Terranova, Michael J., Kharidia, Khush M., Oliver, Robert J., Mandyam, Chitra D.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316047/
https://ncbi.nlm.nih.gov/pubmed/30487415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci8120208
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