Notch1 mutations are drivers of oral tumorigenesis

Disruption of NOTCH1 signaling was recently discovered in head and neck cancer. This study aims to evaluate NOTCH1 alterations in the progression of oral squamous cell carcinoma (OSCC) and compare the occurrence of these mutations in Chinese and Caucasian populations. We used a high-throughput-PCR-b...

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Détails bibliographiques
Publié dans:Cancer Prev Res (Phila)
Auteurs principaux: Izumchenko, Evgeny, Sun, Kai, Jones, Sian, Brait, Mariana, Agrawal, Nishant, Koch, Wayne, McCord, Christine L., Riley, David R., Angiuoli, Samuel V., Velculescu, Victor E., Jiang, Wei-Wen, Sidransky, David
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383685/
https://ncbi.nlm.nih.gov/pubmed/25406187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0257
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