Development of Phenotypic and Transcriptional Biomarkers to Evaluate Relative Activity of Potentially Estrogenic Chemicals in Ovariectomized Mice

BACKGROUND: Concerns regarding potential endocrine-disrupting chemicals (EDCs) have led to a need for methods to evaluate candidate estrogenic chemicals. Our previous evaluations of two such EDCs revealed a response similar to that of estradiol (E(2)) at 2 hr, but a less robust response at 24 hr, si...

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Vydáno v:Environ Health Perspect
Hlavní autoři: Hewitt, Sylvia C., Winuthayanon, Wipawee, Pockette, Brianna, Kerns, Robnet T., Foley, Julie F., Flagler, Norris, Ney, Elizabeth, Suksamrarn, Apichart, Piyachaturawat, Pawinee, Bushel, Pierre R., Korach, Kenneth S.
Médium: Artigo
Jazyk:Inglês
Vydáno: NLM-Export 2015
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383572/
https://ncbi.nlm.nih.gov/pubmed/25575267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1307935
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