The Natural Estrogenic Compound Diarylheptanoid (D3): In Vitro Mechanisms of Action and in Vivo Uterine Responses via Estrogen Receptor α

Background: Diarylheptanoid (D3) isolated from the medicinal plant, Curcuma comosa, has estrogenic activity. Objective: We aimed to elucidate the mechanism(s) of D3 action and compare it with that of 17β-estradiol (E(2)) using both in vitro and in vivo uterine models. Methods: We used human uterine...

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Autori principali: Winuthayanon, Wipawee, Piyachaturawat, Pawinee, Suksamrarn, Apichart, Burns, Katherine A., Arao, Yukitomo, Hewitt, Sylvia C., Pedersen, Lars C., Korach, Kenneth S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Institute of Environmental Health Sciences 2013
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620745/
https://ncbi.nlm.nih.gov/pubmed/23552522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1206122
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