Liver Injury Indicating Fatty Liver but Not Serologic NASH Marker Improves under Metformin Treatment in Polycystic Ovary Syndrome

Objective. Polycystic ovary syndrome (PCOS) is associated with obesity and insulin resistance (IR), key features of nonalcoholic steatohepatitis (NASH). Cytokeratin 18 fragments (M30) have been established as a serum marker for NASH. The insulin sensitizer metformin improves hepatic IR. This study e...

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Dettagli Bibliografici
Pubblicato in:Int J Endocrinol
Autori principali: Tan, Susanne, Vollmar, Nils, Benson, Sven, Sowa, Jan-Peter, Bechmann, Lars P., Gerken, Guido, Fuhrer, Dagmar, Canbay, Ali
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383456/
https://ncbi.nlm.nih.gov/pubmed/25873949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/254169
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