Liver Injury Indicating Fatty Liver but Not Serologic NASH Marker Improves under Metformin Treatment in Polycystic Ovary Syndrome

Objective. Polycystic ovary syndrome (PCOS) is associated with obesity and insulin resistance (IR), key features of nonalcoholic steatohepatitis (NASH). Cytokeratin 18 fragments (M30) have been established as a serum marker for NASH. The insulin sensitizer metformin improves hepatic IR. This study e...

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Detalhes bibliográficos
Publicado no:Int J Endocrinol
Main Authors: Tan, Susanne, Vollmar, Nils, Benson, Sven, Sowa, Jan-Peter, Bechmann, Lars P., Gerken, Guido, Fuhrer, Dagmar, Canbay, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383456/
https://ncbi.nlm.nih.gov/pubmed/25873949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/254169
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