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IPEX Syndrome, FOXP3 and Cancer

In this review, we introduce the IPEX syndrome and its relationship with germline mutations of the FOXP3 gene. We then describe the multiple functional roles of FOXP3 in regulatory T cells and epithelial cells as well as in IPEX syndrome and tumor progression. Potential mechanisms of FOXP3 inactivat...

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Detalles Bibliográficos
Publicado en:J Syndr
Main Authors: Liu, Runhua, Li, Silin, Yang, Wei-Hsiung, Wang, Lizhong
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383293/
https://ncbi.nlm.nih.gov/pubmed/25844400
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