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Analyses of tumor suppressor genes in germ-line mouse models of cancer

Tumor suppressor genes are critical regulators of growth and functioning of cells, whose loss of function contributes to tumorigenesis. Accordingly, analyses of the consequences of their loss of function in genetically engineered mouse models have provided important insights into mechanisms of human...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Protoc
Main Authors: Wang, Jingqiang, Abate-Shen, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383238/
https://ncbi.nlm.nih.gov/pubmed/25086022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.top069773
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