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High-fat Diet Causes Bone Loss in Young Mice by Promoting Osteoclastogenesis through Alteration of the Bone Marrow Environment

Obesity is a severe health problem in children, afflicting several organ systems including bone. However, the role of obesity on bone homeostasis and bone cell function in children has not been studied in detail. Here we used young mice fed a high-fat diet (HFD) to model childhood obesity and invest...

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Detalhes bibliográficos
Publicado no:Calcif Tissue Int
Main Authors: Shu, Lei, Beier, Eric, Sheu, Tzong, Zhang, Hengwei, Zuscik, Michael, Puzas, J. Edward, Boyce, F. Brendan, Mooney, A. Robert, Xing, Lianping
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383048/
https://ncbi.nlm.nih.gov/pubmed/25673503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-015-9954-z
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