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Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design
Organometallic complexes are effective hydrogenation catalysts for organic reactions. For example, Noyori-type ruthenium complexes catalyse reduction of ketones by transfer of hydride from formate. Here we show that such catalytic reactions can be achieved in cancer cells, offering a new strategy fo...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Pub. Group
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4383003/ https://ncbi.nlm.nih.gov/pubmed/25791197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7582 |
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