SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation

Short interspersed nuclear elements (SINEs), such as Alu, spread by retrotransposition, which requires their transcripts to be copied into DNA and then inserted into new chromosomal sites. This can lead to genetic damage through insertional mutagenesis and chromosomal rearrangements between non-alle...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Varshney, Dhaval, Vavrova-Anderson, Jana, Oler, Andrew J., Cowling, Victoria H., Cairns, Bradley R., White, Robert J.
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382998/
https://ncbi.nlm.nih.gov/pubmed/25798578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7569
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