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Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch

Complex genomes utilize insulators and boundary elements to help define spatial and temporal gene expression patterns. We report that a genome-wide B1 SINE (Short Interspersed Nuclear Element) retrotransposon (B1-X35S) has potent intrinsic insulator activity in cultured cells and live animals. This...

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Bibliografiska uppgifter
Huvudupphovsmän: Román, Angel Carlos, González-Rico, Francisco J., Moltó, Eduardo, Hernando, Henar, Neto, Ana, Vicente-Garcia, Cristina, Ballestar, Esteban, Gómez-Skarmeta, José L., Vavrova-Anderson, Jana, White, Robert J., Montoliu, Lluís, Fernández-Salguero, Pedro M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044856/
https://ncbi.nlm.nih.gov/pubmed/21324874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.111203.110
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