Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch

Complex genomes utilize insulators and boundary elements to help define spatial and temporal gene expression patterns. We report that a genome-wide B1 SINE (Short Interspersed Nuclear Element) retrotransposon (B1-X35S) has potent intrinsic insulator activity in cultured cells and live animals. This...

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Main Authors: Román, Angel Carlos, González-Rico, Francisco J., Moltó, Eduardo, Hernando, Henar, Neto, Ana, Vicente-Garcia, Cristina, Ballestar, Esteban, Gómez-Skarmeta, José L., Vavrova-Anderson, Jana, White, Robert J., Montoliu, Lluís, Fernández-Salguero, Pedro M.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2011
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044856/
https://ncbi.nlm.nih.gov/pubmed/21324874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.111203.110
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