Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota

Obesity is a pandemic disease associated with many metabolic alterations and involves several organs and systems. The endocannabinoid system (ECS) appears to be a key regulator of energy homeostasis and metabolism. Here we show that specific deletion of the ECS synthesizing enzyme, NAPE-PLD, in adip...

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Udgivet i:Nat Commun
Main Authors: Geurts, Lucie, Everard, Amandine, Van Hul, Matthias, Essaghir, Ahmed, Duparc, Thibaut, Matamoros, Sébastien, Plovier, Hubert, Castel, Julien, Denis, Raphael G. P., Bergiers, Marie, Druart, Céline, Alhouayek, Mireille, Delzenne, Nathalie M., Muccioli, Giulio G., Demoulin, Jean-Baptiste, Luquet, Serge, Cani, Patrice D.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382707/
https://ncbi.nlm.nih.gov/pubmed/25757720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7495
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