Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism

OBJECTIVE: To examine the role of hepatocyte myeloid differentiation primary-response gene 88 (MyD88) on glucose and lipid metabolism. DESIGN: To study the impact of the innate immune system at the level of the hepatocyte and metabolism, we generated mice harbouring hepatocyte-specific deletion of M...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Duparc, Thibaut, Plovier, Hubert, Marrachelli, Vannina G, Van Hul, Matthias, Essaghir, Ahmed, Ståhlman, Marcus, Matamoros, Sébastien, Geurts, Lucie, Pardo-Tendero, Mercedes M, Druart, Céline, Delzenne, Nathalie M, Demoulin, Jean-Baptiste, van der Merwe, Schalk W, van Pelt, Jos, Bäckhed, Fredrik, Monleon, Daniel, Everard, Amandine, Cani, Patrice D
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Gut Microbiota
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529962/
https://ncbi.nlm.nih.gov/pubmed/27196572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2015-310904
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