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Design and evaluation of a peptide-based immunotoxin for breast cancer therapeutics
Immunotoxins are chimeric proteins comprising a specific cellular targeting domain linked to a cytotoxic factor. Here we describe the design and use of a novel, peptide-based immunotoxin that can initiate selective cytotoxicity on ErbB2-positive cells. ErbB2 is a receptor tyrosine kinase that is ove...
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| Pubblicato in: | FEBS Open Bio |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382514/ https://ncbi.nlm.nih.gov/pubmed/25853036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.03.005 |
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