Загрузка...
Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2
This study utilized pharmacological activation of Nrf2 with oleanolic acid (OA, 22.5 mg/kg, sc for 4d) and the genetic Nrf2 activation (Nrf2-null, wild-type, and Keap1-HKO mice) to examine the role of Nrf2 in protection against phalloidin hepatotoxicity. Mice were given phalloidin (1.5 mg/kg, ip for...
Сохранить в:
| Опубликовано в: : | Toxicol Lett |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382455/ https://ncbi.nlm.nih.gov/pubmed/25280775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2014.09.027 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|