Exosomes Secreted from GATA-4 Overexpressing Mesenchymal Stem Cells Serve as a Reservoir of Anti-Apoptotic microRNAs for Cardioprotection

BACKGROUND: Exosomes play an important role in intercellular signaling and exert regulatory function by carrying bioactive molecules. This study investigated the cardioprotective capabilities of exosomes derived from mesenchymal stem cells (MSC) overexpressing GATA-4 (MSC(GATA-4)) and its underlying...

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Detalhes bibliográficos
Publicado no:Int J Cardiol
Main Authors: Yu, Bin, Kim, Ha Won, Gong, Min, Wang, Jingcai, Millard, Ronald W., Wang, Yigang, Ashraf, Muhammad, Xu, Meifeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382384/
https://ncbi.nlm.nih.gov/pubmed/25590961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2014.12.043
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