Exosomes Secreted from CXCR4 Overexpressing Mesenchymal Stem Cells Promote Cardioprotection via Akt Signaling Pathway following Myocardial Infarction

Background and Objective. Exosomes secreted from mesenchymal stem cells (MSC) have demonstrated cardioprotective effects. This study examined the role of exosomes derived from MSC overexpressing CXCR4 for recovery of cardiac functions after myocardial infarction (MI). Methods. In vitro, exosomes fro...

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Bibliographic Details
Published in:Stem Cells Int
Main Authors: Kang, Kai, Ma, Ruilian, Cai, Wenfeng, Huang, Wei, Paul, Christian, Liang, Jialiang, Wang, Yuhua, Zhao, Tiejun, Kim, Ha Won, Xu, Meifeng, Millard, Ronald W., Wen, Zhili, Wang, Yigang
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436515/
https://ncbi.nlm.nih.gov/pubmed/26074976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/659890
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