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Street-Experienced Peripheral B cells Traffic to the CNS in Multiple Sclerosis

High-throughput sequencing of immunoglobulin repertoires in patients with multiple sclerosis reveals that antigen-experienced B cells traffic between the peripheral lymph nodes and the central nervous system, suggesting the involvement of peripheral immunity in the autoimmune pathogenesis of multipl...

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Bibliographic Details
Published in:Sci Transl Med
Main Authors: Lu, Daniel R., Robinson, William H.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382305/
https://ncbi.nlm.nih.gov/pubmed/25100737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3009919
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