Comparative Effectiveness of Tocilizumab with either Methotrexate or Leflunomide in the Treatment of Rheumatoid Arthritis

OBJECTIVE: In agreement with EULAR recommendations, a DMARD in combination with a biotherapy is the reference treatment because of the superior long-term clinical and radiographic outcomes. Methotrexate (MTX) is the cornerstone of combination therapy but is in some cases contra-indicated or poorly t...

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Bibliographic Details
Published in:PLoS One
Main Authors: Narváez, Javier, Díaz-Torné, César, Magallares, Berta, Hernández, Maria Victoria, Reina, Delia, Corominas, Héctor, Sanmartí, Raimon, de la Serna, Arturo Rodriguez, Llobet, Josep Maria, Nolla, Joan M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382296/
https://ncbi.nlm.nih.gov/pubmed/25830224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123392
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