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Differential effects of leflunomide and methotrexate on cytokine production in rheumatoid arthritis
Background: T cells have a pivotal role in RA. Leflunomide inhibits pyrimidine biosynthesis, to which T cells are especially susceptible, and therefore may have a different cytokine profile than methotrexate. Materials and methods: Serum samples of 100 patients with RA, treated with leflunomide (n =...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1755136/ https://ncbi.nlm.nih.gov/pubmed/15115713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2003.014738 |
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