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Bringing home the bacon? The next step in cardiac sodium channelopathies

Mutations in SCN5A, which encodes the α subunit of the major cardiac sodium channel Na(V)1.5, are associated with multiple cardiac arrhythmias, including Brugada syndrome. It is not clear why mutations in SCN5A result in such a variety of cardiac phenotypes, and introduction of analogous Scn5a mutat...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Wilde, Arthur A.M., Postema, Pieter G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382245/
https://ncbi.nlm.nih.gov/pubmed/25500878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80014
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