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Bringing home the bacon? The next step in cardiac sodium channelopathies
Mutations in SCN5A, which encodes the α subunit of the major cardiac sodium channel Na(V)1.5, are associated with multiple cardiac arrhythmias, including Brugada syndrome. It is not clear why mutations in SCN5A result in such a variety of cardiac phenotypes, and introduction of analogous Scn5a mutat...
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Publicado no: | J Clin Invest |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382245/ https://ncbi.nlm.nih.gov/pubmed/25500878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80014 |
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