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High-Throughput In Vivo Genotoxicity Testing: An Automated Readout System for the Somatic Mutation and Recombination Test (SMART)

Genotoxicity testing is an important component of toxicity assessment. As illustrated by the European registration, evaluation, authorization, and restriction of chemicals (REACH) directive, it concerns all the chemicals used in industry. The commonly used in vivo mammalian tests appear to be ill ad...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lombardot, Benoit, Oh, Chun-Taek, Kwak, Jihoon, Genovesio, Auguste, Kang, Myungjoo, Hansen, Michael Adsett Edberg, Han, Sung-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382174/
https://ncbi.nlm.nih.gov/pubmed/25830368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121287
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