Tobacco Smoke Activates Human Papillomavirus 16 p97 Promoter and Cooperates with High-Risk E6/E7 for Oxidative DNA Damage in Lung Cells

We have previously shown a functional interaction between human papillomavirus type 16 (HPV-16) E6 and E7 oncoproteins and cigarette smoke condensate (CSC) in lung cells suggesting cooperation during carcinogenesis. The molecular mechanisms of such interaction, however, remain to be elucidated. Here...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Peña, Nelson, Carrillo, Diego, Muñoz, Juan P., Chnaiderman, Jonás, Urzúa, Ulises, León, Oscar, Tornesello, Maria L., Corvalán, Alejandro H., Soto-Rifo, Ricardo, Aguayo, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382149/
https://ncbi.nlm.nih.gov/pubmed/25830243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123029
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