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Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions in vitro and in vivo

Oxidative-stress-induced necrosis is considered to be one of the main pathological mediators in various neurological disorders, such as brain ischaemia. However, little is known about the mechanism by which cells modulate necrosis in response to oxidative stress. In the present study, we showed that...

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Podrobná bibliografie
Vydáno v:Biochem J
Hlavní autoři: Guo, Xing, Sesaki, Hiromi, Qi, Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381936/
https://ncbi.nlm.nih.gov/pubmed/24758576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131438
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