Adjudin Targeting Rabbit Germ Cell Adhesion as a Male Contraceptive: A Pharmacokinetics Study

Adjudin (1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide; formerly called AF-2364) has been shown to inhibit spermatogenesis by disrupting anchoring junctions at the Sertoligerm cell interface. This, in turn, leads to germ cell loss from the seminiferous epithelium, and transient infertility. Ad...

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Foilsithe in:J Androl
Main Authors: HU, GUO-XIN, HU, LU-FENG, YANG, DAI-ZHENG, LI, JUN-WEI, CHEN, GUO-RONG, CHEN, BING-BING, MRUK, DOLORES D., BONANOMI, MICHELE, SILVESTRINI, BRUNO, CHENG, C. YAN, GE, REN-SHAN
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381873/
https://ncbi.nlm.nih.gov/pubmed/18802200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2164/jandrol.108.004994
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