Adjudin Targeting Rabbit Germ Cell Adhesion as a Male Contraceptive: A Pharmacokinetics Study

Adjudin (1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide; formerly called AF-2364) has been shown to inhibit spermatogenesis by disrupting anchoring junctions at the Sertoligerm cell interface. This, in turn, leads to germ cell loss from the seminiferous epithelium, and transient infertility. Ad...

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Bibliografiska uppgifter
I publikationen:J Androl
Huvudupphovsmän: HU, GUO-XIN, HU, LU-FENG, YANG, DAI-ZHENG, LI, JUN-WEI, CHEN, GUO-RONG, CHEN, BING-BING, MRUK, DOLORES D., BONANOMI, MICHELE, SILVESTRINI, BRUNO, CHENG, C. YAN, GE, REN-SHAN
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381873/
https://ncbi.nlm.nih.gov/pubmed/18802200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2164/jandrol.108.004994
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