Ghrelin Increases Beta-Catenin Level through Protein Kinase A Activation and Regulates OPG Expression in Rat Primary Osteoblasts

Ghrelin, by binding growth hormone secretagogue receptor (GHS-R), promotes osteoblast proliferation but the signaling mechanism of GHS-R on these cells remains unclear. Since canonical Wnt/β-catenin pathway is critically associated with bone homeostasis, we investigated its involvement in mediating...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Endocrinol
Autori principali: Mrak, Emanuela, Casati, Lavinia, Pagani, Francesca, Rubinacci, Alessandro, Zarattini, Guido, Sibilia, Valeria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381660/
https://ncbi.nlm.nih.gov/pubmed/25866509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/547473
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi