GCN5 inhibits XBP-1S-mediated transcription by antagonizing PCAF action

Cellular unfolded protein response (UPR) is induced when endoplasmic reticulum (ER) is under stress. XBP-1S, the active isoform of X-box binding protein 1 (XBP-1), is a key regulator of UPR. Previously, we showed that a histone acetyltransferase (HAT), p300/CBP-associated factor (PCAF), binds to XBP...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Lew, Qiao Jing, Chu, Kai Ling, Chia, Yi Ling, Soo, Benjamin, Ho, Jia Pei, Ng, Chew Har, Kwok, Hui Si, Chiang, Cheng-Ming, Chang, Yao, Chao, Sheng-Hao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381594/
https://ncbi.nlm.nih.gov/pubmed/25426559
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