RNA interference screening identifies a novel role for PCTK1/CDK16 in medulloblastoma with c-Myc amplification

Medulloblastoma (MB) is the most common malignant brain tumor in children and is associated with a poor outcome. cMYC amplification characterizes a subgroup of MB with very poor prognosis. However, there exist so far no targeted therapies for the subgroup of MB with cMYC amplification. Here we used...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Ćwiek, Paulina, Leni, Zaira, Salm, Fabiana, Dimitrova, Valeriya, Styp-Rekowska, Beata, Chiriano, Gianpaolo, Carroll, Michael, Höland, Katrin, Djonov, Valentin, Scapozza, Leonardo, Guiry, Patrick, Arcaro, Alexandre
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381582/
https://ncbi.nlm.nih.gov/pubmed/25402633
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