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Targeting Voltage Gated Sodium Channels Na(V)1.7, Na(V)1.8, and Na(V)1.9 for Treatment of Pathological Cough

Recent advances in our understanding of voltage-gated sodium channels (Na(V)s) lead to the rational hypothesis that drugs capable of selective blockade of Na(V) subtypes may be a safe and effective strategy for the treatment of unwanted cough. Among the nine Na(V) subtypes (Na(V)1.1–Na(V)1.9), the a...

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Vydáno v:Lung
Hlavní autoři: Muroi, Yukiko, Undem, Bradley J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381564/
https://ncbi.nlm.nih.gov/pubmed/24272479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00408-013-9533-x
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