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Silencing efficacy prediction: a retrospective study on target mRNA features
Post-transcriptional gene silencing is a widely used method to suppress gene expression. Unfortunately only a portion of siRNAs do successfully reduce gene expression. Target mRNA secondary structures and siRNA-mRNA thermodynamic features are believed to contribute to the silencing activity. However...
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| Gepubliceerd in: | Biosci Rep |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Portland Press Ltd.
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4381284/ https://ncbi.nlm.nih.gov/pubmed/25702798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20140147 |
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