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Targeting Cyclin-Dependent Kinases in Human Cancers: From Small Molecules to Peptide Inhibitors

Cyclin-dependent kinases (CDK/Cyclins) form a family of heterodimeric kinases that play central roles in regulation of cell cycle progression, transcription and other major biological processes including neuronal differentiation and metabolism. Constitutive or deregulated hyperactivity of these kina...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Peyressatre, Marion, Prével, Camille, Pellerano, Morgan, Morris, May C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381256/
https://ncbi.nlm.nih.gov/pubmed/25625291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers7010179
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