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The Roles of Akt Isoforms in the Regulation of Podosome Formation in Fibroblasts and Extracellular Matrix Invasion

Mesenchymal cells employ actin-based membrane protrusions called podosomes and invadopodia for cross-tissue migration during normal human development such as embryogenesis and angiogenesis, and in diseases such as atherosclerosis plaque formation and cancer cell metastasis. The Akt isoforms, downstr...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Eves, Robert, Oldham, Robyn, Jia, Lilly, Mak, Alan S.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381253/
https://ncbi.nlm.nih.gov/pubmed/25575302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers7010096
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