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iRNA-seq: computational method for genome-wide assessment of acute transcriptional regulation from total RNA-seq data

RNA-seq is a sensitive and accurate technique to compare steady-state levels of RNA between different cellular states. However, as it does not provide an account of transcriptional activity per se, other technologies are needed to more precisely determine acute transcriptional responses. Here, we ha...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Madsen, Jesper Grud Skat, Schmidt, Søren Fisker, Larsen, Bjørk Ditlev, Loft, Anne, Nielsen, Ronni, Mandrup, Susanne
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381047/
https://ncbi.nlm.nih.gov/pubmed/25564527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1365
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