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Leucine-Rich Repeat Kinase 2 Modulates Neuroinflammation and Neurotoxicity in Models of Human Immunodeficiency Virus 1-Associated Neurocognitive Disorders
Leucine-rich repeat kinase 2 (LRRK2) is the single most common genetic cause of both familial and sporadic Parkinson's disease (PD), both of which share pathogenetic and neurologic similarities with human immunodeficiency virus 1 (HIV-1)-associated neurocognitive disorders (HAND). Pathologic LR...
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Pubblicato in: | J Neurosci |
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Autori principali: | , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Society for Neuroscience
2015
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4381000/ https://ncbi.nlm.nih.gov/pubmed/25834052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0650-14.2015 |
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