The New Small-Molecule Mixed-Lineage Kinase 3 Inhibitor URMC-099 Is Neuroprotective and Anti-Inflammatory in Models of Human Immunodeficiency Virus-Associated Neurocognitive Disorders

Human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND) is a significant source of disability in the HIV-infected population. Even with stringent adherence to anti-retroviral therapy, >50% of patients living with HIV-1 will develop HAND (Heaton et al., 2010). Because suppres...

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Main Authors: Marker, Daniel F., Tremblay, Marie-Ève, Puccini, Jenna M., Barbieri, Justin, Gantz Marker, Mary A., Loweth, Colin J., Muly, E. Chris, Lu, Shao-Ming, Goodfellow, Val S., Dewhurst, Stephen, Gelbard, Harris A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682381/
https://ncbi.nlm.nih.gov/pubmed/23761895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0598-13.2013
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