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Aberrant DNA hypermethylation reduces the expression of the desmosome-related molecule periplakin in esophageal squamous cell carcinoma

Periplakin (PPL), a member of the plakin family of proteins that localizes to desmosomes and intermediate filaments, is downregulated in human esophageal squamous cell carcinoma (ESCC). Little is known, however, about the molecular mechanism underlying the regulation of PPL expression and the contri...

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Bibliografske podrobnosti
izdano v:Cancer Med
Main Authors: Otsubo, Takeshi, Hagiwara, Teruki, Tamura-Nakano, Miwa, Sezaki, Takuhito, Miyake, Oki, Hinohara, Chihaya, Shimizu, Toshio, Yamada, Kazuhiko, Dohi, Taeko, Kawamura, Yuki I
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380967/
https://ncbi.nlm.nih.gov/pubmed/25583674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.369
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